Njengakwimeko "yokuzibandakanya ngokwesondo," into ethi "transgender" nayo ngokwayo inengxaki, kuba ayinasiseko senzululwazi okanye kuvumelwano phakathi kweentshukumo ze-LGBT. Kwangelo xesha, alithandabuzeki elokuba kwimibutho yaseNtshona inqanaba lezinto ezihamba ngesantya esiphikisayo esibonisa ukuba inyani ye-biology ikhuphuke kakhulu kule minyaka idlulileyo. Ukuba kwi-2009 unyaka phakathi Tavistock Clinic Ulutsha lwe-97 lujongile kwi-dysphoria yesini, ke kulo nyaka uphelileyo inani labo laba ngaphezu kwamawaka amabini.